Plummer-Vinson Syndrome with Improvement After Iron Repletion

Valerian Mwenda1, Jackson Njuguna2, Ancent Nzioka2.

  1. Department of Internal Medicine and Endoscopy, Consolata Hospital Nkubu

  2. Department of Pathology, School of Medicine, Kenyatta University.

Correspondence to: Dr. Valerian Mwenda P.O Box 205-60200 Meru, Kenya.



Plummer-Vinson Syndrome (PVS) is a rare disorder characterized by upper esophageal webs and iron deficiency anemia and is even more uncommon among people of African descent. We report a case of this syndrome in a middle-aged black woman, which improved on iron-repletion therapy alone. The patient presented with long-standing dysphagia and symptomatic anemia. Gastrointestinal endoscopy revealed an upper esophageal web arising from the anterior wall. She was started on iron therapy daily and after 2 months both the dysphagia and anemia had improved significantly. Therefore, though this is a relatively rare condition in Africa, it still warrants being part of the differential diagnosis for dysphagia especially in the setting of anemia.


Keywords: Plummer-Vinson Syndrome, Anemia, Dysphagia, Endoscopy

Ann Afr Surg. 2016;13(2): 81-3.



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