ssk_logo.png

The Annals of African Surgery is the official publication of the Surgical Society of Kenya.

 

All content copyright © 2020 Annals of African Surgery.

ISSN (print): 1999-9674; ISSN (online): 2523-0816

Main Office Location: Menelik Medical Centre, Menelik Road, off Ngong Road, Nairobi. First floor.

Telephone: +254715260499

Email: info@annalsofafricansurgery.com.

 

The content on this site is intended for health professionals. Advertisements on this site do not constitute a guarantee or endorsement by the journal, Association, or publisher of the quality or value of such product or of the claims made for it by its manufacturer.

70.png
69.jpg
hinari_header_en.png
Non-Palpable Invasive Lobular Carcinoma Initially Diagnosed by Inguinal Lymph Node Biopsy

Mohammad Zuhdy, Mona Zaky, Reham Alghandour, Gena Abdelazeem, Omar Hamdy, Abdelhadi Shebl Mansoura University, Egypt.

Correspondence to: Dr. Omar Hamdy, Mansoura University, Mansoura, Egypt. Email: omarhamdy87@gmail.com

Summary

Metastasis to the inguinal lymph nodes or the vulva from breast cancer is a very rare event with very few cases reported in literature. A 38-year-old lady with a complaint of progressive abdominal enlargement. Physical examination was unremarkable apart from abdominal enlargement and enlarged right inguinal lymph node. Radiology showed marked ascites, omental thickening, bilateral small ovarian masses, suspicious right inguinal lymph node (LN) as well as breast fibrocystic disease. Cytological examination of the ascitic fluid revealed malignant cells. Core needle biopsy from the inguinal LN suggested metastatic breast carcinoma. Breast MRI showed heterogeneous fibroglandular tissue and moderate parenchymal enhancement. Random core needle biopsies from the breast led to the diagnosis of invasive lobular carcinoma. The patient received 8 cycles of docetaxel/ carboplatin protocol, with partial response. Next, she was maintained on hormonal treatment (Anastrazole) till the ascites re-accumulated. Vulvar nodules appeared whose biopsy revealed infiltration by the same tumoral tissue. She received 6 cycles of Endoxan and Pharmarubicin till regression was achieved, and then she was subjected to Exemestane. Thorough clinical assessment including of all lymph nodes basins and gynecological assessment is crucial in all breast cancer patients particularly those with invasive lobular subtypes.

 

Key words: Breast neoplasms, Lobular, Vulva, Vulvar metastasis, Neoplasm metastasis

Ann Afr Surg. 2019; 17(1):***

DOI: http://dx.doi.org/10.4314/aas.v16i1.*

Conflicts of Interest: None

Funding: None

© 2019 Author. This work is licensed under the Creative Commons Attribution 4.0 International License.

  • Twitter
  • Facebook Social Icon
  • LinkedIn